10th EUROPEAN CONFERENCE ON TETRASPANINS
28-30 September 2022 Prague
10th EUROPEAN CONFERENCE ON TETRASPANINS
28-30 September 2022 Prague
Programme
(only for participants)
| Wednesday, September 28, 2022 | |
|---|---|
| 13:30-15:00 | Registration with coffee |
| 15:00-15:15 | Welcome by Ivana Hálová (organizer) and Petr Dráber (IMG director) |
| 15:15-16:00 | Keynote lecture: Tetraspanins: from worms to regulators of immune cell recruitment Mark Wright, Monash University, Australia |
| Session 1 – TETRASPANINS and IMMUNITY I Chairs: Fedor Berditchevsky, Ivana Hálová | |
| 16:00-16:25 | Tetraspanin CD53 controls T cell immunity through regulation of CD45RO stability, mobility, and function Annemiek van Spriel, Radboud University, The Netherlands |
| 16:25-16:50 | CD9 in epithelial wound healing Peter Monk, University of Sheffield, UK |
| 16:50-17:15 | Tetraspanin CD82 regulates dormancy signaling within the bone marrow niche Jennifer Gillette, University of New Mexico, USA |
| Flash poster session Chair: Michael Tomlinson | |
| 17:20-18:15 | Flash Poster Session – 2 minutes each |
| Welcome party | |
| 18:15-22:00 | Dinner at IMG |
| Thursday, September 29, 2022 | |
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| Session 2 – TETRASPANINS and IMMUNITY II Chairs: Peter Monk, Annemiek van Spriel | |
| 9:00-9:25 | Tetraspanin CD53 in mast cell biology Ivana Hálová, IMG, Czech Republic |
| 9:25-9:50 | Human Papillomavirus associated tetraspanin assemblies Luise Florin, University Mainz, Germany |
| 9:50-10:10 | Single cell characterization of metabolic markers in adipose tissue macrophages in obesity Monika Bambousková, Washington University in St. Luis, USA |
| 10:10-10:25 | Tetraspanin anchors as versatile molecular tools for SARS CoV-2-immunization and diagnostic Daniel Ivanusic, Robert Koch-Institute, Germany |
| 10:25-10:40 | Tetraspanin 3: a novel player in protein trafficking in plasma cells? Fabian Schwerdtfeger, Radboud University, The Netherlands |
| 10:40-11:15 | Coffee break |
| Session 3 – TETRASPANINS in CANCER Chairs: Jennifer Gillette, Eric Rubinstein | |
| 11:15-11:40 | Tetraspanins and oxysteroles: a new axis of intercellular communication in regulation of the immune microenvironment in breast cancer Fedor Berditchevski, University of Birmingham, UK |
| 11:40-12:05 | Anti-Lymphoma Efficacy of the 5A6 antibody in a Human-CD81-epitope Knock-In mouse Shoshana Levy, Stanford University, USA |
| 12:05-12:25 | TETRASPANIN 8 contribution in colon physiology and pathophysiology Francoise Degoul, INSERM, France |
| 12:25-12:40 | Identification of a novel CD151 interaction partner on B cells Philipp Hagemann, Radboud University, The Netherlands |
| 12:40-12:55 | Tetraspanin 6 (Tspan6) has a role in the attachment of F. nucleatum subspecies to colorectal cancer cells Onalenna Neo, University of Birmingham, UK |
| 12:55-14:10 | Lunch & Poster Session |
| 14:10-14:25 | The role of the Tetraspanin 6 (Tspan6) in regulating the immune microenvironment in Inflammatory Breast Cancer (IBC) Jing Zhang, University of Birmingham, UK |
| 14:25-14:40 | Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37 Rens Peeters, Radboud University, The Netherlands |
| 14:40-14:55 | Investigating the role of tetraspanin Tspan15 in cancer Rhiannon Moss, University of Birmingham, UK |
| Session 4 – TETRASPANINS and their INTERACTION PARTNERS I Chairs: Andrew Kruse, Luise Florin | |
| 15:00-15:25 | The inventory of TEM ingredients at the cell membrane – relationship between abundance and nano-clustering Thorsten Lang, University of Bonn, Germany |
| 15:25-15:50 | Made to Measure: Structural Basis for Selective Proteolysis of ADAM10 Substrates at Membrane-Proximal Sites Stephen Blacklow, Harvard Medical School, USA |
| 15:50-16:15 | Six scissors – ADAM10 regulation by TspanC8s Mike Tomlinson, University of Birmingham, UK |
| 16:15-16:40 | CD82, a membrane organizer of the plasma membrane Pierre-Emmanuel Milhiet, Centre de Biologie Structurale, France |
| 16:40-17:45 | Poster session with refreshment |
| Free evening | |
| Friday, September 30, 2022 | |
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| Session 5 – TETRASPANINS and their INTERACTION PARTNERS II Chairs: Stephen Blacklow, María Yáñez-Mó | |
| 8:45-9:10 | The Tetraspanin-JAM connection: A set screw of integrin function Klaus Ebnet, University of Münster, Germany |
| 9:10-9:35 | Subcellular trafficking of CD9 and CD81 Eric Rubinstein, INSERM, France |
| 9:35-10:00 | Structure and regulation of the B cell co-receptor complex Andrew Kruse, Harvard Medical School, USA |
| 10:00-10:20 | Fibronectin decoration of clustered syndecan-1 is required for CD9-mediated staphylococcal adhesion Luke Green, University of Sheffield, UK |
| 10:20-10:50 | Coffee break |
| 10:50-11:05 | Glycosylation differentially affects immune-specific tetraspanins CD37 and CD53 Sjoerd van Deventer, Radboud University, The Netherlands |
| 11:05-11:20 | Modulation of AMPA-type glutamate receptors by proteins from the tetraspanin family Amina Becic, Ruhr University Bochum, Germany |
| 11:20-11:35 | Juno and CD9 protein network organization in oolemma of mouse egg captured by 3D STED imaging Michaela Frolíková, IBT, Czech Republic |
| Session 6 – Extracellular vesicles Chairs: Pierre-Emmanuel Milhiet, Klaus Ebnet | |
| 11:40-12:05 | Tetraspanin CD9 connects endosomal compartment dynamics and extracellular vesicle secretion with mitophagy in melanoma cells María Yáñez-Mó, Autonomous University of Madrid, Spain |
| 12:05-12:30 | Tumor EV heterogeneity and functional consequences Lorena Martin-Jaular, Institute Curie, France |
| 12:30-12:50 | PDZ proteins interact with tetraspanins & syndecans and regulate the production, composition and uptake of extracellular vesicles Pascale Zimmermann, INSERM, France |
| 12:50-14:05 | Lunch & Discussions |
| 14:05-14:25 | Molecular dissection of how ALIX drives EV biogenesis Robert Piper, University of Iowa, USA |
| 14:25-14:40 | CD63 Regulates Cholesterol storage within endosomes and its intercellular distribution via exosomes Mickaël Couty, Université de Paris, France |
| 14:40-15:10 | Conclusions & Plans & Good bye |